Calculator for risk-stratification with neonatal jaundice.
Neurotoxicity risk factors:
- Isoimmune Hemolytic Disease
- G6PD deficiency
- Asphyxia
- Significant lethargy
- Temperature instability
- Sepsis
- Acidosis
- Albumin < 3 g/dL
Hyperbilirubinemia risk factors:
- Bilirubin in high-risk zone
- Jaundice in first 24 hours of life
- ABO incompatibility with...
- Positive direct Coombs
- or Known hemolytic disease
- or Elevated ETCO2
- Gestational age 35-36 weeks
- Sibling had phototherapy
- Cephalohematoma / bruising
- Exclusive breastfeeding, particularly with poor feeding or weight loss
- East Asian Race
Blackmon LR et al. Research on Prevention of Bilirubin-Induced Brain Injury and Kernicterus: National Institute of Child Health and Human Development Conference Executive Summary. Pediatrics. 2004; 114: 229-233.