Risk stratification for patients with acute pulmonary embolism.
Meta-analysis review of PESI demonstrated the following:
- Class I: 1.2% risk of serious adverse event; 0.5% risk of death
- Class III: 3.5% risk of serious adverse event; 6% risk of death
- Sensitivity for PE-related mortality: 95%
**Serious adverse events were defined as any of the following: nonfatal recurrent PE, nonfatal recurrent DVT, nonfatal bleeding, or delayed homodynamic instability.
Aujesky D et al. Derivation and validation of a prognostic model for pulmonary embolism. Am J Respir Crit Care Med. 2005; 172(8):1041-1046.
Zhou, XY et al. The prognostic value of pulmonary embolism severity index in acute pulmonary embolism: a meta-analysis. Respiratory Research. 2012;13:111.